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Old 05-30-2008, 05:22 AM
Larry Boy Larry Boy is offline
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Join Date: Sep 2007
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Quote:
Originally Posted by Chris Noble View Post
The protective effect of aspirin against heart disease could not have been discovered by stumbling across it. It is necessary to conduct large scale double blind randomised trials in order to pick it up.

By contrast the antipyretic and analgesic effects of salicylic acid are strong enough that they could be stumbled across.

I am definitely not saying that small effect sizes are not real but I am extremely skeptical of claims involving small effect sizes that do not have any basis in established science especially where very minor problems in experimental design can account for the observed effect.
That's fair enough, I guess.
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